Exhibits Index The exhibits listed in the accompanying index to exhibits are filed as part of, or incorporated by reference into, this Annual Report on Form 10-K. 3.1 Amended and Restated Certificate of Incorporation. 10-Q 001-37792 3.1 August 15, 2016 3.2 Amended and Restated Bylaws. 10-Q 001-37792 3.2 August 15, 2016 4.1 Description of Securities X 4.2 Indenture dated April 27, 2021, among NantHealth, Inc., NaviNet, inc. and U.S. Bank National Association 8-K 001-37792 4.1 April 28, 2021 10.1.1+ Second Amended and Restated NantOmics Exclusive Reseller Agreement, dated as of September 20, 2016, by and between the Registrant and NantOmics, LLC. 10-Q 001-37792 10.1 November 10, 2016 10.1.2+ Amended and Restated NantOmics Exclusive Reseller Agreement, dated as of May 9, 2016, by and between the Registrant and NantOmics, LLC. S-1/A 333-211196 10.1 June 1, 2016 10.1.3+ Amendment No. 2 to Second Amended and Restated NantOmics Exclusive Reseller Agreement, dated as of April 23, 2019, by and between the Registrant and NantOmics, LLC. 10-Q 001-37792 10.1.2 May 9, 2019 10.1.4 Amendment No. 3 to Second Amended and Restated NantOmics Exclusive Reseller Agreement dated as of December 31, 2020. 8-K 001-37792 10.2 January 5, 2021 10.2+ NantHealth License Agreement, dated June 19, 2015, by and between the Registrant and NantOmics, LLC, as amended. S-1/A 333-211196 10.2 June 1, 2016 10.3# 2016 Equity Incentive Plan, as Amended and Restated, and related form agreement. S-8 333-239326 99.1 June 19, 2020 10.4# 2016 Executive Incentive Compensation Plan. S-1 333-211196 10.13 May 6, 2016 10.5 Amended and Restated Promissory Note, between Registrant and Nant Capital LLC, dated May 9, 2016. S-1/A 333-211196 10.18 May 11, 2016 10.6 Amended and Restated Promissory Note, between Registrant and NantOmics, LLC, dated May 23, 2016. S-1/A 333-211196 10.19 May 24, 2016 10.7 Side Letter Agreement, between Registrant and NantWorks, LLC, dated May 22, 2016. S-1/A 333-211196 10.21 May 23, 2016 10.8 Indenture, dated December 21, 2016, between NantHealth, Inc. and U.S. Bank National Association. 8-K 001-37792 10.2 December 21, 2016 10.10 Purchase Agreement, dated December 15, 2016, by and among NantHealth, Inc. and J.P. Morgan Securities LLC and Jefferies LLC, as representative of the initial purchasers named therein. 8-K 001-37792 10.1 December 21, 2016 10.11 Purchase Agreement, dated December 15, 2016, by and between NantHealth, Inc. and Cambridge Equities, L.P. 8-K 001-37792 10.2 December 21, 2016 10.12 Second Amended and Restated Promissory Note, dated December 15, 2016, by and between NantHealth, Inc. and Nant Capital LLC. 8-K 001-37792 10.3 December 21, 2016 10.13 Asset Purchase Agreement dated as of August 3, 2017, between Allscripts Healthcare Solutions, Inc. and NantHealth Inc. 8-K 001-37792 2.1 August 31, 2017 10.14+ Amendment No.1 to Second Amended and Restated Reseller Agreement, dated December 18, 2017, by and between NantHealth, Inc. and NantOmics, LLC. 10-K 001-37792 10.14 March 16, 2018 Incorporated by Reference Number Exhibit Title Form File No. Exhibit Filing Filed Date Herewith - 143 -
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